And here is a chilling review of Long Covid neurologic complications:
Nervous system consequences of COVID-19
• 20 Jan 2022 • Vol 375, Issue 6578 • pp. 267-269 • DOI: 10.1126/science.abm2052
https://www.science.org/doi/10.1126/science.abm2052
I really, really, really want more data and info about this. What the risks are, who is most at risk, what the prevalence is, etc. You would think that this would be very important to know before opening everything up and exposing people to this potential issue.
I look at many scientific papers and these days a good number are about Covid. I don´t think more than a fraction of a percent is of interest to the general public.
Covid induced brain injury, its neuropsychiatric consequences and possible development of mental health problems are of public interest and I am going to give you four reasons off the top of my head:
1) in brain injury, there is a window of time during which rehabilitation taking advantage of neuroplasticity is essential to optimize functional outcomes and possibly improve mental health outcomes
2) people with behavioral, mental health or cognitive issues face some of the most difficult to overcome obstacles in gaining access to health care in the US
3) Long Covid is by definition a chronic illness. US medicine is generally very good with management of acute illnesses but far less so with chronic illnesses affecting individuals who are less useful economically because of said illness
4) no matter what happens, the cost of neurologic Long Covid is going to be astronomical and now is the time to address the issue proactively. The alternative would be waiting until action becomes reactive by necessity and even more expensive with even worse outcomes
I see that you are interested in exercise and might be interested in the most interesting paper I read today - not of general public interest but very interesting nevertheless.
They studied 10 patients with Long Covid and exercise intolerance with invasive cardiopulmonary exercise testing. The main finding is that there was a deficiency in extracting oxygen from the blood.
Without going into the details too much, the most likely explanation is not cyanide poisoning or similar but a shunting away (bypassing) of circulating blood from muscle tissue that is being starved of oxygen. In other words, the heart is pumping but the blood comes back with most of its oxygen undelivered while some muscles are under severe oxygen deprivation.
Interestingly, that is a pattern of shock called distributive shock which again is the typical pattern of resuscitated septic shock.
The issue is most likely caused by a Covid induced small fiber neuropathy (another example of Covid induced neurologic disease), that is, the small nerves controlling the distribution of blood flow by either constricting or relaxing small blood vessels to optimize oxygen delivery, are gone or do not function anymore. Think of rice fields and little canals and gates to regulate flow, and a situation were the little gates stop functioning and heavy rains are coming.
So these patients develop a sort of shock state as soon as they start exerting themselves - no wonder that they feel terrible and sometimes require days to recover from exertion.
Persistent Exertional Intolerance After COVID-19
Insights From Invasive Cardiopulmonary Exercise Testing
Chest. 2022 Jan; 161(1): 54–63.
doi: 10.1016/j.chest.2021.08.010
PMCID: PMC8354807
PMID: 34389297
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354807/pdf/main.pdf