I have some Banana Republic slacks (from the thrift store) that are machine washable. TBH I shop at the thrift store, read the tags, and sometimes just throw things in the wash anyway (as mentioned - delicate/cold cycles, and air dried) They don't look as sharp as dry cleaned stuff, mostly because I don't iron them, but works for me.
In the costuming world, spraying with vodka is the way to get rid of bacteria without damaging the garment. I've been known to do that to delicate clothing and/or when I didn't feel like doing laundry that day.