I heard the first 10 mins, and really to me is was a slick commercial for their Give Directly system.
I do endorse the idea of giving charity directly to those who need it. There's no reason for a middle man to be involved... the irony is that Give Directly is the middleman. Heh. Pretty slick.
I think there are legitimate reasons to need an agency to facilitate cash transfers (if you decide that cash transfers are how you would like your charity dollars spent). When I choose where to give, I'm thinking about how to maximize my donated money's impact, which I would argue is an extremely Mustachian thing to do. In that regard, third world countries are my best bet, by leaps and bounds. But since I live in a first world country (and you probably do as well), how the heck am I going to find these extremely poor third-worlders to give my money to? And if I plan to give to charity on an ongoing basis, I'd like them to be doing some research to figure out whether it's actually working, so that, if it turns out it's not, I can stop giving them my money and start giving it to someone who's getting better results).
Give Directly is one of GiveWell's top recommended charities, and GiveWell is
extremely choosy about who they endorse, basing their recommendations primarily on proven effectiveness of the intervention. Skepticism is a good thing when investigating a charity, but this one checks out very well to me.