We sacrificed on house to get the short commute for DH. I was a stay at home mom to three toddlers, and he was going to grad school and commuting. We had moved pretty far out to get an affordable, nice home for our growing family - but the longer we lived there, the worse his commute got. It was 45 minutes when we moved out there, and by the time we sold our house, it was over an hour each way.
So, we downsized from 1900 square feet, two car garage, full basement, new construction (I really did love that house!) and bought a tiny fixer-upper (really, tear down, LOL), 1200 square feet, 3 bed, 1.5 bath - 2 miles from DH's work.
This house was the pits for years and years, until we could finally afford to gut the kitchen and main bath 2 years ago - BUT - we all love his non-commute. He comes home for lunch sometimes - or if I need him for anything, he can be here in minutes. Absolutely priceless for our family. Plus, he isn't exhausted from being in the car - and our cars have very low mileage and should last basically forever ;)
No regrets, it was absolutely the right choice for our family.