As I mentioned, in our previous home we had to bathrooms, but only used the one upstairs in practice. So only one bathroom to clean. The other one was mostly used by occasional guests.
In our current home, we have a large bathroom with bathtub adjacent to the bedroom. We even enter the bedroom through the bathroom (design flaw, is you ask me). But that it the bathroom where we brush our teeth and where DH washed himself at the sink most of the time, and takes his occasional bath.
I on the other hand, love to shower. But that big bathroom doesn't have a shower where you can stand under. You can only shower sitting in the bathtub, which is a bit hopeless. So I mostly use bathroom number 2 where there is a shower. There is also room to place a bubble bath in the corner, but we haven't bothered to install one. That bathroom is also closest to our living room, so we use it as the toilet during the rest of the day.
Therefore, even living there with only 2 people, we still use 2 bathrooms and both need to be cleaned regularly. I do that probably weekly, or at least when I notice dust or other uncleanliness. I use maybe 15-20 minutes per bath for a basic wash (sinks, mirrors, scales, toilets, bathtub and flat surfaces), only dry dusting the floor. I generally never need to wipe the tiles on the walls. Occasionally I also scrub the shower floor and wet wipe the whole floor, clean the lamps above the mirrors and wash the shower glass walls. Those glass walls are normally dried on the inside after showering.