I think your expectations are too high. Specifically, you seem to think that there is some perfect home out there, that is in a bustling neighborhood but quiet and safe, in nature but without loud birds, etc. When in the reality, you are usually trading one set of problems for another. So if you make decisions looking only at the problems you are getting rid of, you are always going to be unhappy with your choices, because you will always be surprised by the new problems you weren't looking for before. The grass is always greener over the septic tank, you know. Or to put it more succinctly:
Happiness: Reality - Expectations > 0
Misery: Expectations - Reality > 0
Everything comes with a tradeoff. The only way to try to make a good decision is to consider and rank all of your priorities, look as hard and objectively as you can at the pros and cons of each decision, and then make the decision that gives you the most of what you want -- without expecting that decision to be trouble-free. And even then you get it wrong sometimes, because human beings are ridiculously bad at identifying what actually makes them happy.
And along those lines, I think your search for quiet and safety led you to ignore a real source of happiness that you already had: a community. What tends to make people happy is social connections -- a feeling of belonging. You said it yourself: you liked feeling the hustle and bustle, feeling in the middle of a community, even if you didn't always like what came along with it. Now you feel isolated. That is misery-inducing -- especially since you work from home!! You need to make yourself a new community, stat, so you can start feeling like you belong where you are now.
Finally, keep in mind that change itself can be stressful, even if you like the end result. Any time you move, you have to take a lot more time and mental energy re-learning things that used to be routine -- what's the fastest way to/from school, when do you really want to avoid the main drag because of traffic, what's the best grocery store and how do they organize their aisles, where's the stupid drug store/gas station, etc. etc. etc. It's easy to take for granted how easy these things can be when they're on autopilot and require zero brain cells, so when you have to start over from scratch, it feels like a huge burden. And then of course you quickly move past the honeymoon phase and stop noticing all of the things that are better, and start noticing all of the new problems that you weren't aware of, so now the mental burden feels even bigger. And if you suffer from anxiety and depression, that burden is magnified even more, because life just feels so overwhelming for a while (and so easy before, in retrospect, because you didn't have to deal with any of this stuff!).
So give yourself time to settle in. And if the change or the birds or whatever are exacerbating your anxiety, go to the doctor, now, and get some meds/new meds. Things will settle in to a new routine sooner or later, but you might need some help getting over the hump.