I can honestly say "No."
Now that you mention it, I'm not sure I would use that metric.
Net worth is a valuable number, but it is somewhat divorced from "Can I afford the ongoing payments on a house?"
Naturally, one can sell one's assets, but sometimes the cost can be quite high to do so. And, equally naturally, you're most likely to need to when it would be least beneficial to do so.
Cash flow is also really important. In terms of affordability (for a personal residence), I found that a mortgage at 100% of my income to be very affordable. At 200% of income it was affordable but money was tight. Those percentages will vary a bit based on the interest rate that's being charged, but since the prices tend to go up when credit is cheap, that's not necessarily a benefit. (If you buy a $100,000 house and get 20% underwater, that's way better than a $300,000 house that's 20% underwater.)