I'm reporting in as someone with an active autoimmune flare who just got the second shot of Moderna.
First shot husband and I got no side effects but very sore arm.
The day after the second shot, my husband was totally wiped and kind of achy and stiff. He would work for an hour, then go for a 2-hour nap, rinse and repeat all day long. The second night after the shot he ran a very slight fever on and off. This morning he is still tired but otherwise no symptoms.
I had a much tougher experience. First night (about 12 hours after the shot) I woke around 3 a.m. with severe body-clenching chills (no fever interestingly) and mild nausea and severe body aches. After a couple hours, I took ibuprofen and was able to sleep. Woke up the next morning feeling like I'd been run over by a truck...could hardly move for stiffness, headache, severe body aches, and continued nausea. Got up, took more ibuprofen, ate some toast, started to feel slightly better. By early afternoon the day after the shot I was pretty sure I was over it, but I was wrong. At 4 pm it was like I hit a brick wall, chills started again, body aches worsened, and I became utterly exhausted and retreated to a super hot bath or bed the rest of the day. Woke up this morning with the nausea, headache, and joint pain gone but still utterly stiff and exhausted. I expect I will have to nap some more today as well.
I've never had anything like this kind of reaction to any other vaccination. Obviously my immune system responded like a five alarm fire to this vaccine, so that's good. I need to keep in mind how hard I am hit when/if this vaccination becomes an annual shot...need to plan for 2 days of illness afterward.
I had a bit of an autoimmune rash flare yesterday evening, but nothing out of the ordinary for me. If anything further pops up in terms of autoimmune stuff in the next couple weeks I will report in.