Author Topic: Ambient temperature and cancer  (Read 5222 times)

dailycycle

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Ambient temperature and cancer
« on: November 30, 2013, 10:48:17 AM »
I know it's silly to change one's lifestyle based on the little snippets of scientific studies reported on in the news.  So often they are contradicted shortly after (blueberries, coffee, red wine = superfood, for instance).  Then again, anyone dealing with cancer or a history of cancer might want to consider any behavioral modification which could affect tumor growth.  To that end, I found this article interesting:

http://www.economist.com/news/science-and-technology/21590352-studies-may-be-skewed-laboratory-mice-being-kept-too-cool-mice-and-men

It suggests when your body is working to keep itself warm less energy is going to fighting cancer.  When I read it I thought of those here who keep their houses at 50 degrees, as well as my family's history of doing the same and their current battles with cancer.

gooki

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Re: Ambient temperature and cancer
« Reply #1 on: November 30, 2013, 11:21:49 AM »
This might be the answer I need to convince the wife to move to a warmer climate :)

Russ

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Re: Ambient temperature and cancer
« Reply #2 on: November 30, 2013, 11:48:50 AM »
Sure, and you could only eat every third day and live to be 150
Just live your life

dragoncar

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Re: Ambient temperature and cancer
« Reply #3 on: November 30, 2013, 01:53:23 PM »
I didn't read the study, but I'm a bit skeptical the issue is "less energy is going to fight cancer".  More likely, higher metabolism a are correlated with cancer.  Colder weather = higher metabolism = higher oxidative stress on the body.

Consider the flip side that rats who live close to starvation tend to outlive their well fed counterparts.

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Re: Ambient temperature and cancer
« Reply #4 on: November 30, 2013, 02:16:50 PM »
Saw this study in another article (the economist) that covered this question. Study author said it doesn't apply to people. We can put on sweaters but mice can't.

Bakari

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Re: Ambient temperature and cancer
« Reply #5 on: November 30, 2013, 02:48:41 PM »
I didn't read the study, but I'm a bit skeptical the issue is "less energy is going to fight cancer".  More likely, higher metabolism a are correlated with cancer.  Colder weather = higher metabolism = higher oxidative stress on the body.

Consider the flip side that rats who live close to starvation tend to outlive their well fed counterparts.

That's what I would expect too.
The other example isn't really a "flip" side, its the same issue - restricted calories leads to slower metabolism, which means slower cell aging and cell growth which means it takes longer for the telomeres to run out.  Once telomeres run out, continued cell division starts causing random mutations.  A random mutation which stops the cells mechanism to know when to stop reproducing is cancer (the cell just keeps growing past the point of self-replacement, indefinitely).

So, moving as little as possible, and eating as little as possible, would presumably not only combat cancer, but slow all forms of aging.
But of course, lack of exercise also causes all sorts of disease. 
The health detriments of not exercising seem to outweigh the benefits of slower metabolism, so there is really no good reason to try to apply any of this to real life.

Ziggurat

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Re: Ambient temperature and cancer
« Reply #6 on: November 30, 2013, 03:40:49 PM »
...restricted calories leads to slower metabolism, which means slower cell aging and cell growth which means it takes longer for the telomeres to run out.

Telomere shortening is old school ... latest is DNA methylation:
http://www.nature.com/news/chemical-clock-tracks-ageing-more-precisely-than-ever-before-1.13981

Point is ... we don't really know that much ... yet.

dragoncar

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Re: Ambient temperature and cancer
« Reply #7 on: November 30, 2013, 04:51:08 PM »
I didn't read the study, but I'm a bit skeptical the issue is "less energy is going to fight cancer".  More likely, higher metabolism a are correlated with cancer.  Colder weather = higher metabolism = higher oxidative stress on the body.

Consider the flip side that rats who live close to starvation tend to outlive their well fed counterparts.

That's what I would expect too.
The other example isn't really a "flip" side, its the same issue - restricted calories leads to slower metabolism, which means slower cell aging and cell growth which means it takes longer for the telomeres to run out.  Once telomeres run out, continued cell division starts causing random mutations.  A random mutation which stops the cells mechanism to know when to stop reproducing is cancer (the cell just keeps growing past the point of self-replacement, indefinitely).

So, moving as little as possible, and eating as little as possible, would presumably not only combat cancer, but slow all forms of aging.
But of course, lack of exercise also causes all sorts of disease. 
The health detriments of not exercising seem to outweigh the benefits of slower metabolism, so there is really no good reason to try to apply any of this to real life.

I just look at it as another reason for moderation.  I'll exercise 30 min a day or whatever, but I'm not doing any marathons or trying to build excessive muscle bulk.

Bakari

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Re: Ambient temperature and cancer
« Reply #8 on: November 30, 2013, 05:05:00 PM »
...restricted calories leads to slower metabolism, which means slower cell aging and cell growth which means it takes longer for the telomeres to run out.

Telomere shortening is old school ... latest is DNA methylation:
http://www.nature.com/news/chemical-clock-tracks-ageing-more-precisely-than-ever-before-1.13981

Point is ... we don't really know that much ... yet.

That is very interesting, (and thanks for the link) - but I don't see how this new research contradicts any of the older theories.  Its talking about tracking age, not explaining how age contributes to cancer.  So they can both be true.

Ziggurat

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Re: Ambient temperature and cancer
« Reply #9 on: November 30, 2013, 06:22:56 PM »
...restricted calories leads to slower metabolism, which means slower cell aging and cell growth which means it takes longer for the telomeres to run out.

Telomere shortening is old school ... latest is DNA methylation:
http://www.nature.com/news/chemical-clock-tracks-ageing-more-precisely-than-ever-before-1.13981

Point is ... we don't really know that much ... yet.

That is very interesting, (and thanks for the link) - but I don't see how this new research contradicts any of the older theories.  Its talking about tracking age, not explaining how age contributes to cancer.  So they can both be true.

I wasn't trying to contradict; sorry if it came across that way. Yes they can both be true, or partially true. There is some correlation to cancer, though, in that cancer tissues were shown to speed up this clock.

I was just adding to the comments about not taking scientific snippets too seriously in modifying our daily behaviors. There's still much more to come in these areas. This one example looks very interesting and promising to me.


Rural

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Re: Ambient temperature and cancer
« Reply #10 on: November 30, 2013, 06:39:05 PM »
Well, my completely unscientific take is that people with cancer ought to stay warm if that makes them feel better.

 

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