I can't speak for Audis specifically, but OP, it sounds like you just want us to validate buying (or convince you not to buy) an Audi. I will provide some caveats below, as I have owned vehicles of all different brands and types. All purchased used except one.
In my life, I've had:
-4 Jeeps (1 XJ, 1 TJ, 2 Grand Cherokees); The 4.0L remains one of my favorite engines of all time. Beyond that, there were always little things breaking on Jeeps, but they never left me stranded. Very easy to fix myself.
-1 Dodge (Dart); almost left me stranded but I was able to limp it to get repaired under warranty. Decent car otherwise.
-1 Mazda; some minor electrical gremlins, but otherwise a solid car
-1 BMW; purchased CPO, had the 3.0L turbo which was just a rocket and a blast to drive. I had *GASP* ZERO (0) issues in the 2.5 years I owned it. Sold last year during the used car price craziness for almost what I paid for it.
-2 Fords (well, one was a Mercury). Currently drive an Edge which is probably my favorite vehicle I've owned. It just feels solid, is stupidly quick (2.7L turbo), very versatile, and loaded and comfy.
My experience is not really what you hear about for some of those brands. Point being, most modern cars are solid and will last a long time if maintained. Just do some research, test cars out, and get what you want/what fits in your budget.