Oh for sure. I have some pretty reliable sellers on small orders, $25-50 each. Nothing but cobwebs on the bigger cards ($150-200+). I'm curious about continuing to pick up little cards if they sell so well, that way I always have something getting interest. I mean, if a card sells 6/8 times a year at $50 I'd rather not have it "age up" and go for $100 or $200 and get only one order a year or two years.
Having what we would consider "desirable" cards... high credit limit, long history, etc... may not be what buyers really need. It might be more efficient for them to just show an increase in available credit/lower utilization that a quick $10-$20,000 increase in available credit on a six-month-old card can provide, and at a lower cost.