I think it's great that people try to think about how to lead healthier lifestyles, and I think the paleo/primal thing is interesting as a theory. I also think that it's pretty irrefutable that decreasing overly processed foods is healthier, especially eliminating trans fats, and things that are really dense in high glycemic index carbs.
But the evidence supporting the overarching theory for primal blueprint (of eating/exercising like pre-agricultural humans - if that's even possible) is weak. I find it follows the same basic money-making recipe as the authors of most health/diet fads.
1) Build a diet/exercise concept around a theory that sounds scientific, but is accessible to the general public.
2) Pick data/ideas that fit the theory, and ignore those that don't.
3) Begin marketing.
Does primal/paleo work for people? Sure, but so do the Atkins Diet, the South Beach Diet, the Cabbage Soup diet, the Mediterranean diet, or (the antithesis of Sisson's ideas) low fat diets with lots of cardio. All of these are completely different from paleo, but all of which have people restricting some part of their diet and ultimately changing the balance of calories in to calories out. They all also have studies showing improvements in a variety of health outcomes.
If the primal diet/exercise concepts work for you, that's great. But, they are definitely not the only way, and probably not the healthiest way to get the same results. But, the marketing and science really turn me off.
Sisson strongly markets body image. His website is peppered with photos of his bare chest and his wife's abs. I checked out a few of his books from the library, and was had trouble getting past the contrived Grok/Korg stories, the cherry-picked photos/data, and the general tone. A photo in one of his books has a caption along the lines of: "look how ripped these aborgines are". There are
other ways to get ripped, and they all focus on 2 things. Resistance exercise and dropping body fat by reducing calories. Of course the aborigines were ripped - hunter gatherers used their bodies and didn't have easy access to calories. If you started doing more resistance training, and either burned more or took in fewer calories on paleo/primal, then of course you will look more ripped. It has nothing to do with using coconut oil instead of canola oil.
All the body image stuff is a red flag to me, and no different from TV ads for buns of steel/ab cruncher/
tug-toner (trust me, you'll be glad you clicked on it). Looking ripped is nice, but a good physique comes with fitness - and six-pack abs have more to do with low body fat than any other meaningful measure of fitness.
Finally, publishing books and a blog doesn't require peer review (which you could say of almost all diet/nutrition books/blogs), so there's no mechanism to even try to get the evidence right.
Not trying to be a hater, and if following this "blueprint" works for you, that's great. But, it's neither representative of how paleolithic people ate/lived, nor is his idea of eliminating foods developed agriculture on very strong scientific ground.