[...] It's also nice peace of mind to have 100k plus in a taxable account, that's a few years worth of a mortgage payment to absorb market volatility
That may be a false peace of mind and illustrates the biggest (IMO) risk of a levered strategy.
Assuming you're invested in equities you have liquidity exposure: Specifically, let's say your equities go down by 30%. If you're forced to dip into your now $70k account to make payments on your debt, you're going to have to sell depressed stock. Even if the market recovers after a short time and has great overall returns, your forced liquidation can have a severe effect on returns (because you were forced to sell at the worst time possible).
Hedging against this requires maintaining a larger cash (or near-cash) emergency fund, which has a cost itself (not accounted for in calculations I've seen in this thread so far).
Sizing this fund is tough, too, because the market could stay depressed for years.
I'm not saying the leverage investment is necessarily a bad idea, but it's not as simple as just assuming because stock market returns are greater than interest rates, it's a sure thing.