Depending on what you are trying to do, you could just do some reading on the vanguard website, in particular checking out their asset allocation online tool to help you decide what to invest in. You can also give them a call to say you want to open an account and ask for advice from the person on the other line. Your question is vague enough that it is not clear whether you are new to investing all together. If so, check out JL Collins stock market series to educate yourself on the fundamentals.