Energy Savings: Sometimes things like insulating your house, energy saving appliances etc can be tax deductible (of course, don't be stupid, only claim this if you were planning to insulate anyhow).
Rentals: If you rent out a room in your house, 1/2 of utilities and repairs to that portion of the house can be deducted against the income which you received.
Work Expenses: If you pay for internet and cell phones and your "regularly" defined by IRS use those for work, those can be deducted as work related expenses. If you travel more than 50 miles for work, then the difference between the distance from your work, and the travel can be deducted at a standard per mile rate.
Education: Certain Education costs (including the purchase of materials) can be deducted as well, so keep receipts and look into those when the time comes.
Sales Tax: If you bought something really expensive, your sales taxes might be higher than your income tax, so just double check that.
Moving for a job: All moving expenses including mileage on your car are deductible provided you are moving for a job.
Most of my tips are having to with itemized deductions. I got a few thousand dollar refund (when usually I owe) last year, because it so happened that we practically only spent money on tax deductible things last year.