I can sympathize. I think, sometimes, about my parents. They may have liked their jobs or hated them, but to them, it wasn't their identity. It was simply a means to make a living and support a family. So, it was only 8 hours a day.
That puts it into perspective, no? For some people. You don't have to like it, but it is something you are getting paid to do. I have a book called "It's called WORK for a REASON." By Larry Winget, I think.
On the other hand, if you are sick and miserable - if it's affecting your home life, and you aren't able to fix that - then it's time to reconsider.
I like what I do but 2012 and 2013 and 1/2 of 2014 were freaking miserable for me at work, due to company changes and management changes and ... my career literally tanked, and it was awful.
So I took a step back, decided just to "do good work" and find time for interesting stuff at work (learn new skills), and try not to worry about stuff that I couldn't change. In 2014 I focused on my health, exercise, and weight loss. Well, my career is still in the toilet but I am learning new skills and I'm 26 pounds lighter.
My recommendation is to try and help him "make the best of it". And if he truly can't, then you have already done the right thing by giving him options. Just KNOWING that he has options may help him at work.