Alameda is a very nice place to live. It's charming and pleasant without being pretentious. Lots of families live there, and you'll be safe just about anywhere. It's very easy to get around Alameda on a bicycle - it's flat and compact with many bike lanes. There are walking trails by the water, locally owned stores, farmer's markets, etc.
The main stumbling block is the cost of living, particularly housing. If you're planning on living in Alameda, you'd probably be looking at a minimum of $1500/month rent for a one-bedroom apartment. You can forget about buying a house in Alameda on a salary of $80K to $100K, although a condo might be doable.
You might be able to cut housing costs by sharing a house or apartment with a roommate, or you could move to an area with a lower cost of living like the neighboring city of Oakland. However, Oakland has a bad rap for a reason, so you'd need to be careful of where you live and go.
You should probably also be aware that traffic in the Bay Area is a nightmare, especially during rush hour. If there's any way you can live and work in the same community, it will greatly increase your quality of life.
Good luck with the job interview!