I generally do individual items as packaged deals often don’t meet all my preference boxes (preferred airline, hotel location, etc.), but have found good packaged deals from time to time. You just have to try different combinations to see what gives you the best value within your parameters e.g. flight+hotel+car vs flight+hotel only vs flight+Car only.
Get an idea of what the individual costs are and then compare with the package deals. Recently, I’ve also noticed that for car rentals, better deals can be had via online portals vs going directly with the same car rental company.
Depending on where you are going, you may also want to check out vacation packages offered by the big 3 airlines. If you are a Costco member, that’s another option to look into. I’ve found some good deals via those from time to time especially for popular destinations.
Your biggest factor in putting together a good deal overall is going to be flexibility in terms of travel dates/days. Sometimes increasing or decreasing the trip by a day or leaving/coming back on a weekday vs weekend or just traveling another weekend can make a huge difference in the overall price. Google flights calendar view or +/- days option in kayak will give you some good comparative data points that you can use to put together the other components.