Without knowing where your husband is going to find work, I think it's not especially safe to assume you will be able to remain a one car family. If you manage to find a place that is walkable/bikeable to your work, then it would work out, but part of the problem with San Diego is that it is hugely sprawled. People live as far South as the Mexican boarder, and even as far north as Temecula (which isn't officially SD at all). And there are workplaces and living areas that far as well. And traffic is getting worse and worse, so commutes are getting more and more difficult to manage.
Generally, the further east you go, the cheaper things get, but also the further away you are from most of the places you might want to go. If you don't mind sharing, what part of SD is the company in? Downtown, La Jolla, somewhere else?
Lastly, someone mentioned the medical leave stuff, but I recall there being limits on how long you must have been employed to get them, so make sure you look in to that. I can't recall the particulars, so I could be misremembering. And I have no idea if that clock would start from when you arrive in CA, or if because this is a transfer that might factor in. Just make sure you aren't expecting something you won't get.