Nope.
To be fair though, I typically use ground beef as more of a flavouring when cooking. I add it to more than twice the amount of fried mushrooms/onions/garlic, grated carrots, peppers, and a whole bunch of spices for pasta sauce. When I make burgers, it's cut about 30% with oats and then eggs breadcrumbs, fried mushrooms/onions, oil, and a whole bunch of spices are added. So, it's not that there's no difference in quality . . . it's that the difference doesn't matter for the way we usually use it. (Actually, the crappier cuts tend to have more fat in them which I like better for both applications.)
As an aside, I make chili with either shredded chili or pulled slow cooked beef . . . and both are infinitely better than using any quality level of ground beef simply because of the satisfying meaty texture of the long strands of meat. Try it, you'll never go back. Especially if you roast some potatoes in some oil, rosemary, and oregano in the oven and then slop the chili over the hot roasted potatoes. Dammit, now I want chili.