The reason I find my software engineering job hard to cope with, is that it abuses my brain. It makes me too one-dimensional, too analytically focused, less mentally balanced, and as a result way less happy. It exacerbates my autistic tendencies, pushes me to isolation as a coping mechanism, and eventually straight up makes me weird. I get less time to be sociable, fit, creative, funny, artistic, etc. It's similar to a runner with bad knees, a construction worker with bad back, etc. It's the consequences of the overuse of your brain. It's not well documented and not widely known, so most engineers just feel that something is wrong but can't explain it perfectly, but it's obvious if you know where to look.