I recently drove two cars "until they died." I define car death as catastrophic failure (would require a replacement or rebuild) of engine or transmission, or non-repairable death by collision.
In May, my 1999 Metro died on the highway. Engine suddenly quit, wouldn't restart no matter what I did (had spark and fuel, starter was clearly trying). Towed it home. Turned out something horrible broke internally in the engine, the crank was locked up, and a spark plug was split in half. Definitely dead. 182,xxx miles. Sold it for $40.
About a week ago, my 1992 Buick Roadmaster wagon died on a different highway. Engine started "acting funny" and then promptly overheated. Oil was full of metal, bearings were essentially gone, really bad knock: engine was toast. Also definitely dead. Shop it was towed to quoted $2,600 for a new engine installed. No thanks. Definitely dead. Sold for scrap. 200,775 miles.
Neither car ever left me stranded except for when they died. We hit a deer in the Buick a year and a half ago at 65mph, but it was "fine" (looked crappy but drove fine) and we kept driving it after replacing a headlight and door glass. The clutch went out in the Metro last year too (was still driveable but had to start it in gear), but I took care of that myself. Many would consider either of those events "death," but we paid them no heed and got another year out of each.