Detroit has some great bargains on houses! You can get some for a dollar!
Oh, you don't want to live in Detroit? :p
My wife & I are in the process of buying a home, but it's not exactly where most people want to live - it's where we want to live. :) And I can work remotely, so we come out ahead with either savings rate or "me working a lot less to raise kids." Either one. Not terribly picky.
Most people wouldn't want to live where we do, though, so land is cheap, and housing is cheap. $140k for 2k sq ft? Why, yes, please. :) (yes, 2k sq ft, I'll be working from home, plus we want a nice board game room)