Hey John,
Canadian here. It honestly depends on how you "hand-picked" them. If you did so using the tenets of value investing by reading the firms financial reports and knowing you didn't overpay for your investments then I wouldn't necessarily sell them. If you handpicked them by hearsay, the news, or randomly, I'd say you're better off selling almost everything and dumping everything into ETFs or low-MER mutual funds depending on how often (and how much) you will continue making deposits.
Personally, I have 80% of my equities portfolio in index funds tracking the TSX, S&P 500 and international stocks, with a speculative dabble into oil I made two years ago which is still earning me 6% dividends.
As for ETFs, you are already on the right track with vanguard, I've got some in VEU, VUS, etc. The rest are still mutual funds with lowish MER.