Thank you for some very thoughtful replies. (I love the Oatmeal and have had that comic posted on my wall for some time!)
I think I may have left some things out. I'm very good at working from home, I do find time to ride here and there and in particular, to coffee shops, libraries, restaurants, etc. I came from a background in nonprofit project and program management and have quickly elevated to a role in policy within my current organization. I'm so much a face to face, people person that a lot of this work is just eating me up. Again, great job, love the mission, but the work just isn't playing to my strengths. It is probably worth mentioning that this job runs on grants and right now there are enough grants to cover my income through December - though my org is very resourceful and gets award big grants constantly.
I am hoping the new job will pay more than I've estimated, but who knows? This job is also, surprisingly considering the paycut, a career step up as I'd be running a small nonprofit. It is one of those opportunities where if I didn't understand nonprofits from working in them and the content so well from years of working in that type of nonprofit I wouldn't be as qualified for the job - so may not be qualified for another role as a nonprofit ED for years to come.
Again, thanks for your thoughts, the blatant outcry that I was pretty much crazy has helped balance my decision some. Second interview is in about 24 hours so I'm hoping to have some concrete numbers to be thinking with soon here.