Your risk tolerance is something only you can comment on. If this was your chance of not getting cancer, or chance of continuing to be able to work until a traditional retirement, most people would probably be squirming in their seats.
Before anyone could really opine, though, you should share some of the assumptions you have put into FireCalc. Have you run your model based on historical average projections? Or have you done your best to guess where we are today: old bull market, growth perhaps faltering, low interest rates, etc.--i.e. less-than-ideal conditions?
If the former, then I would worry. A lot. If the latter, then it might just be pessimistic enough to be a solid guess.
The other half, of course, is what about your withdrawal rate? Is it bare bones, covering just food, clothing, shelter for you, or is 1/4 of it for world travel? The best thing you can do is to control your expenses when the markets are going to crap--that is something most models don't comprehend.
And what about your career or skills? Could you easily rejoin the workforce after a decade on the sidelines? Could you work a side gig for $10k per year, and boost your chances significantly? (Second question would be, would it be worth it to you to do so?)