I've got a pretty good life. If I won a small/medium size lottery, I would probably use it entirely to pay off mortgage, increase college funds, invest the remainder, etc. Boring stuff, maybe some small home remodels, etc.
If I won a large jackpot, I would probably "upgrade" my home, help my family with some needs, maybe replace one or two of our cars (which are 9-10 years old), and would probably scale back or quit working. I'd then devote much of the wealth and my time to philanthropic endeavors to various causes that interest me about healthcare insecurity, the arts, the church, etc.