I'm 47, wife is 41. My target to FIRE would be in three years if we stay in our current city. If we sold and moved to a LCOL area, we could FIRE now. We'll probably work a few more years past that, just to build a large buffer, and I guess it all depends on the markets for the next three years too.
I'm amazed by the number of comments in this post, where health care coverage is one of the main reasons people are staying longer in their jobs. I'm in Canada, so this isn't really much of a consideration, although taxes are much higher, so either way you pay I guess.