No experience with H&R Block brick and mortar, but I have used H&R Block Deluxe for about 20 years, and I have been very happy with it. While it carries the H&R name now, it has been bought and sold a few times through the years. Seamless transitions each time. Owned by Kiplinger at one point.
Wife self employed, Schedule C, SEP IRA contributions, Roth IRA's, rental income, depreciation, lifetime earners credit, savers credit. Handles all of these beautifully. It also has all my information from past years, so data entry is a snap.
Around $40 regular price, but often get it for around $25 on sale, or with something else for free. I always buy the one with the free state return. E-filing the federal is free, but they charge to e-file the state, so print and snail mail it.
They have the ability to call and ask questions included in the price, but I have not used this feature. I would not expect CPA advice through it, only the "temp help" kind of answers you would get from brick and mortar.