My family drives a 2004 Honda Civic Hybrid with only 86,000 miles on it. It's ugly as hell, and it's our only car. I'm keeping it for another decade.
Before I acquired it in 2009, it was a seldom-used pizza delivery car with a gigantic dent that took up the entire driver-side door. The drivers also left cigarette burns in the upholstery. Both of these "big problems" made it cheaper. The dent has been hammered out, but the cigarette burns will be there forever.
We only drive 7-8K miles per year, so this thing's got lots of life left in it.
One big problem: Last year, I had to replace the battery that drives the hybrid system. These things fail after awhile, and if the car is old enough they aren't under warranty anymore. This battery is a specialty item, and it cost me $2500. I paid cash, of course.
Expensive? Yep. But it's cheaper than getting another car, especially considering the low mileage on the current vehicle.
I'd have been better off had this been the normal, non-hybrid version of the Civic, but it was a great deal at the time. It still is, mostly, but having to replace that battery pretty much negates any fuel savings you enjoy from having a hybrid car.