Are you a full time artist? If so, congrats on (hopefully) being in a position where spending $350,000 on *anything* is possible. That's awesome.
Tiny houses are against the grain of current American culture. So you'll have a harder sell when it comes time to sell, unless you're in an area where rich people want to spend that kind of money on a weekend get-away rustic cabin.
I don't know what your other residence options are, but $350,000 is a LOT of money to spend on a place to live.
If you're an artist and can work anywhere, why work somewhere the housing costs $350,000 when you could live somewhere for a tiny fraction of that? There are lots of beautiful places in the world chock full of nice, interesting people.
My wife and I are doing very well financially and we wouldn't spend that kind of money on lodging unless we had no other choice. We live in a $330,000 house but we only paid $228,000 for it, which is pretty much the most I would be willing to go. Took us 4 years to find the right house at the right price and I'm glad we're not on the hook for another $120,000.
I'm hoping the $350,000 cost includes the tiny house, the workshops, and all the various electrical and water hookups you'll need.
PS -- if you find yourself in the Fayetteville, NC area, drop by for a visit. I've always got an extra seat available in my woodshop and metal/glass and pottery studio.