What annoys me is because of the job I do, people (friends, family, acquaintances, total strangers) feel it's OK to say the following:
"So are you loving your job?" (um, do YOU love your job every single moment of every single day?)
If I don't give a super enthusiastic "You bet!! Get to travel the country and blah blah blah" then I get
"Well, you can't keep this up forever, can you?"
Another time I was at a Walmart paying for groceries. The lady at the register said "You're buying some very healthy food here", then she scans a 6-pack of diet Dr Pepper and says "Well, this isn't very healthy..." I smiled as I thought "you cow...". Geez, with running commentary like that, no wonder there's always a huge queue at the self serve registers!