What kind of thing are you looking for? Does it have to be brand-new? Hulu does less original programming than Netflix, but they have a really deep bench of current and past network shows. A few ideas:
If you like warm-hearted comedy: Brooklyn Nine-Nine, Parks and Recreation, The Good Place, Younger, Better Off Ted, Kitchen Confidential, Sirens, Happy Endings
If you like superhero shows: Cloak and Dagger, Runaways, Agent Carter
If you like family drama: This is Us, Parenthood, Bunheads, Friday Night Lights, The O.C.
If you like dark, twisty drama (really dark): The Handmaid's Tale, Top of the Lake, Unreal
If you like mysteries: Veronica Mars (the first season is terrific, the current (fourth) season is excellent, the second and third seasons weren't as good but enjoyable because of the characters)
If you like thrillers: 24 (it got stupid in later seasons, but the first season was great)
If you like medical drama: ER (again, later seasons were not as strong, but the first few were terrific)
If you like fantasy/SF shows: Buffy the Vampire Slayer, Firefly, LOST, Timeless, X-Files